在总装项目以及国家自然科学基金项目的资助下，主要从事微纳光子器件的设计和人工智能的应用研究，在Nature、Appl. Phys. Lett.、Phys. Rev. A、J. Opt. Soc. Am. B、IEEE J. Lightwave Technol. 等一系列刊物上发表相关研究成果。代表作有：

1.Cang, Hu; Labno, Anna; Lu, Changgui Lu, Changgui; Yin, Xiaobo; Liu, Ming; Gladden, Christopher; Liu, Yongmin; Zhang, Xiang ; Probing the electromagnetic field of a 15-nanometre hotspot by single molecule imaging, Nature, 2011, 469(7330)

2.Zhiqiang Zhou, Changgui Lu, Shuhong Xu, Yuan Jiang, Binfeng Yun, Chunlei Wang, Yiping Cui*; Surface states controlled broadband enhancement of two-photon absorption; Applied Physics Letters, 103, 231111,2013

3.Zhengqing Qi; Jie Yao; Liangliang Zhao; Changgui Lu Changgui Lu; Yiping Cui ; Tunable double-resonance dimer structure for surface-enhanced Raman scattering substrate in near-infrared region, Photonics Research, 2015, 3(6): 313-316

4.Changgui Lu*, Zhengqing Qi, Xuefang Hu, Zhenghua Ni, Yiping Cui; Selectively enhanced Raman scattering with triple-resonance nanohole arrays, Optics communications, 452, 494-498, 2019

5.Changgui Lu^*; Shuping Jin; Xuefang Hu; Xiangyue Zhao; Zhengqing Qi; Weidong Chen; Yiping Cui, A region based random multi-pixel search algorithm to improve the binary hologram reconstruction quality, Optics and Lasers in Engineering, 2023, 161(107322)